Hydroxypropyl methyl cellulose CAS#9004-65-3
Excellent water solubility and compatibility with selected organic solvents provide greater flexibility for use in construction, coatings, pharmaceutical, and personal care formulations.
Delivers outstanding film-forming performance after drying, helping improve surface smoothness, adhesion, moisture retention, and overall product stability in end-use applications.
Features reversible sol-gel transformation during heating and cooling, offering reliable thickening, suspension, emulsification, and temperature-responsive performance in various processing systems.
Available in multiple grades with different methoxy and hydroxypropyl content ratios, allowing customized viscosity and performance to meet diverse industrial requirements.
Product Description of Hydroxypropyl Methyl Cellulose CAS#9004-65-3
Hydroxypropyl methyl cellulose (HPMC) is a propylene glycol ether derivative of methyl cellulose, in which hydroxypropyl and methyl groups are linked to the anhydrous glucose ring through ether bonds.
It appears as a white to off-white powder, granules, or grayish fibrous particles, and is available in different grades with varying methoxy and hydroxypropyl content ratios to meet diverse application requirements.
The product is soluble in water and certain organic solvents, while insoluble in ethanol.
Its aqueous solution exhibits surface activity and excellent film-forming properties after drying. In addition, it features a reversible sol-gel transformation during heating and cooling, making it suitable for applications requiring thickening, suspension, and temperature-responsive performance.
Hydroxypropyl methyl cellulose Chemical Properties
| Melting point | 225-230 °C |
| density | 1.39 |
| storage temp. | room temp |
| solubility | H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow |
| form | powder |
| color | White to cream |
| Odor | Odorless |
| PH | 5.0-8.0 |
| biological source | plant |
| Water Solubility | SOLUBLE |
| Merck | 144842 |
| Stability: | Stable. Solid is combustible, incompatible with strong oxidizing agents. |
| EPA Substance Registry System | 2-Hydroxypropyl methyl cellulose (9004-65-3) |
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | NF9125000 |
| F | 46091 |
| TSCA | Yes |
| HS Code | 39129000 |
Product Application of Hydroxypropyl Methyl Cellulose CAS#9004-65-3
Hydroxypropyl Methyl Cellulose (HPMC) is a water-soluble polymer derived from cellulose, widely used as a thickener, binder, film-forming agent, and water-retention additive.
It also serves as a suspension aid, surfactant, lubricant, protective colloid, and emulsifier. In addition, its aqueous solutions exhibit thermal gelation properties, making it suitable for temperature-sensitive formulations.
HPMC offers many excellent properties and is widely used across multiple industries. Typical application examples include:
Food industry: used as an emulsion and foam stabilizer, fat substitute, non-caloric bulking agent, and binder in various food formulations.
Pharmaceutical industry: applied as a dispersing agent, thickener, tablet film-coating material, and in drug preparation systems.
Cosmetics industry: commonly used in hair shampoos, eye makeup products, skincare formulations, and other personal care applications.
