L-Leucine CAS#61-90-5
Essential Amino Acid Source: L-Leucine is one of the eight essential amino acids, making it an important component in nutritional and biochemical applications.
High Biological Relevance: As an aliphatic amino acid found in proteins, it plays a key role in protein composition and related formulations.
Branched-Chain Amino Acid (BCAA) Value: Together with L-isoleucine and L-valine, it belongs to the important branched-chain amino acids (BCAAs) widely used in food, feed, and pharmaceutical industries.
Optical Purity Advantage: The L-form provides the biologically active enantiomer, ensuring suitability for life science and nutritional applications.
Product Description of L-Leucine CAS# 61-90-5
L-Leucine is one of the eight essential amino acids and belongs to the aliphatic amino acid group among the twenty amino acids commonly found in proteins. Together with L-isoleucine and L-valine, it is classified as one of the three branched-chain amino acids (BCAAs). L-Leucine and D-leucine are enantiomers of each other.
L-Leucine Chemical Properties
| Melting point | >300 °C (lit.) |
| alpha | 15.4 º (c=4, 6N HCl) |
| Boiling point | 122-134 °C(Press: 2-3 Torr) |
| bulk density | 300-400kg/m3 |
| density | 1,293 g/cm3 |
| vapor pressure | <1 hPa (20 °C) |
| refractive index | 1.4630 (estimate) |
| FEMA | 3297 | L-LEUCINE |
| Fp | 145-148°C |
| storage temp. | 2-8°C |
| solubility | 1 M HCl: 50 mg/mL |
| form | powder |
| pka | 2.328(at 25℃) |
| color | White to Off-white |
| Odor | at 100.00?%. odorless |
| PH | 5.5-6.5 (20g/l, H2O, 20℃) |
| biological source | plant |
| Optical Rotation | [α]20/D +15.5°, c = 2 in 6 M HCl |
| Water Solubility | 22.4 g/L (20 C) |
| λmax | λ: 260 nm Amax: 0.05 |
| λ: 280 nm Amax: 0.05 | |
| JECFA Number | 1423 |
| Sublimation | 145-148 ºC |
| Merck | 145451 |
| BRN | 1721722 |
| Stability | Stability Moisture and light sensitive. Incompatible with strong oxidising agents. |
| LogP | 0.8 |
| CAS DataBase Reference | 61-90-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Leucine(61-90-5) |
| EPA Substance Registry System | L-Leucine (61-90-5) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | OH2850000 |
| TSCA | Yes |
| HS Code | 29224995 |
| Hazardous Substances Data | 61-90-5(Hazardous Substances Data) |
Product Application of L-Leucine CAS# 61-90-5
L-Leucine is used in amino acid pharmaceuticals, including amino acid infusions and comprehensive amino acid formulations. It is applied in the diagnosis and treatment of children with idiopathic hyperglycemia and glucose metabolism disorders, as well as conditions such as bile liver diseases associated with reduced secretion, anemia, poisoning, muscular dystrophy, poliomyelitis, neuritis, and certain mental disorders.
