Propiconazole CAS#60207-90-1
Broad-Spectrum Fungicide: Effectively controls a wide range of fungal diseases on cereals, nuts, fruits, and other crops.
Versatile Crop Application: Suitable for use on grasses, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, and stone fruits.
Targeted Disease Control: Controls specific pathogens such as Erysiphe graminis, Leptosphaeria nodorum, Puccinia spp., Septoria spp., and others.
Reliable Agricultural Protection: Provides dependable disease management, improving crop health and yield.
Product Description of Propiconazole CAS#60207-90-1
Propiconazole (Pcz), chemically named 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole, is a triazole-class fungicide. It is widely applied in agricultural production across many crops, including seed grasses, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums, and prunes. In cereal crops, it is effective in controlling diseases caused by Erysiphe graminis, Leptosphaeria nodorum, Pseudocerosporella herpotrichoides, Puccinia species, Pyrenophora teres, Rhynchosporium secalis, and Septoria species.
Wheat is one of the most intensively treated crops with fungicides in the United States, and propiconazole accounts for approximately 90% of these applications. The compound is soluble in water at about 110 mg/L, and concentrations up to 24 mg/L have been detected in surface waters affected by agricultural runoff where this fungicide is used.
Propiconazole Chemical Properties
Melting point | <25 °C |
Boiling point | 180°C (0.1 torr) |
density | 1.2700 |
vapor pressure | 5.6 x l0-5 Pa (25 °C) |
refractive index | 1.6100 (estimate) |
Fp | 11 °C |
storage temp. | APPROX 4°C |
solubility | DMF: 33 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.16 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml |
Water Solubility | 100 mg l-1(2O °C) |
pka | 2.94±0.12(Predicted) |
form | Oil |
Specific Gravity | 1.29 (20℃) |
Merck | 13,7910 |
BRN | 9349305 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | STJLVHWMYQXCPB-UHFFFAOYSA-N |
LogP | 3.7 at 25℃ |
CAS DataBase Reference | 60207-90-1(CAS DataBase Reference) |
EPA Substance Registry System | Propiconazole (60207-90-1) |
Safety Information
Hazard Codes | Xn,N,T,F |
Risk Statements | 22-43-50/53-39/23/24/25-23/24/25-11 |
Safety Statements | 36/37-46-60-61-45-16-7 |
RIDADR | UN3082 9/PG 3 |
WGK Germany | 3 |
RTECS | XZ4620000 |
HS Code | 29349990 |
Hazardous Substances Data | 60207-90-1(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 1517 mg/kg (Urech) |
Propiconazole also functions as a strong inhibitor of brassinosteroid (BR) biosynthesis. Studies have shown that it suppresses hypocotyl elongation in cress (Lepidium sativum), an effect that can be reversed through co-application with brassinolide. Based on the molecular structure of Pcz, additional BR inhibitors have been identified, such as 2RS,4RS-1-[2-(4-trifluoromethylphenyl)-4-n-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole.
Commercially, propiconazole is widely marketed as a fungistatic agent (e.g., Banner Maxx®, Syngenta) for the control of a broad spectrum of plant-pathogenic fungi. Its fungistatic mechanism of action is similar to that of uniconazole (Ucz) and paclobutrazol (Pac), involving the inhibition of lanosterol 14α-demethylase (CYP51A1). In addition, propiconazole has been extensively studied for its effects on plants, animals, humans, and the environment. Molecular genetic studies have also examined its impact on Arabidopsis and maize seedlings.
