Neotame CAS#165450-17-9
High Nutrient Absorption :
The nutrients contained in Neotame are easily absorbed by the human body.
Low-Calorie/Calorie-Free:
Neotame is low in energy or has no energy.Diabetic-Friendly & Blood Sugar Stable:
Can be eaten by diabetics and does not cause blood sugar fluctuations.Dental Health & Gut-Friendly:
Does not cause tooth decay and promotes the proliferation of bifidobacteria.
Neotame Product Description (CAS#165450-17-9)
Neotame is a sweetener whose nutrients are readily absorbed by the body. It is low-calorie or calorie-free, making it suitable for diabetics and weight-conscious individuals. Unlike traditional sweeteners, it does not contribute to tooth decay or blood sugar spikes. Additionally, it supports gut health by promoting the growth of beneficial bifidobacteria. As a result, neotame stands as the ideal sweetener choice for health-focused foods.
Parameters
Melting point | 83-85°C |
alpha | D -54.84° (c = 1 in methanol); D20 -39.8° (c = 0.5 in water) |
Boiling point | 565.3±50.0 °C(Predicted) |
density | 1.133±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Chloroform (Sparingly), Ethanol (Sparingly), Ethyl Acetate (Sparingly), Methanol |
pka | pKa1 3.01; pKa2 8.02(at 25℃) |
form | Solid |
color | White to Off-White |
optical activity | [α]/D -41.0±3.0°, c = 0.5 in H2O |
BRN | 8352678 |
Stability: | Hygroscopic |
InChI | InChI=1/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/s3 |
InChIKey | HLIAVLHNDJUHFG-HOTGVXAUSA-N |
SMILES | C(=O)([C@@H](NCCC(C)(C)C)CC(O)=O)N[C@@H](CC1=CC=CC=C1)C(OC)=O |&1:2,15,r| |
LogP | 3.834 (est) |
Safety Information
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29242990 |
Hazardous Substances Data | 165450-17-9(Hazardous Substances Data) |
Neotame Product Application (CAS#165450-17-9)
Neotame serves as a high-intensity sweetener and flavor enhancer, approved for use in various foods—excluding meat and poultry products. With a sweetness potency 7,000–13,000 times greater than sugar, it delivers a clean, pure sweet taste. Structurally, it is derived from a dipeptide formed by the amino acids aspartic acid and phenylalanine.
This versatile sweetener can be seamlessly blended with both nutritive sweeteners (e.g., sucrose, high fructose corn syrup) and other high-intensity sweeteners (e.g., aspartame, sucralose). Its applications span diverse food categories, including beverages, baked goods, desserts, and cereals. Additionally, it enhances flavors in specific systems, such as mint-flavored chewing gum, where it amplifies taste profiles without adding calories.



