Epsilon-polylysine CAS# 28211-04-3
Broad-Spectrum Antibacterial: Produced through Streptomyces fermentation, ε-Polylysine exhibits strong antibacterial properties, particularly effective against Gram-positive bacteria, even at low concentrations (as low as 5 ppm).
Stable and Versatile: The polymer is stable under various pH and heat conditions, making it suitable for use in a wide range of applications without losing its efficacy.
Natural and Safe: With a molecular weight between 3600-4300, ε-Polylysine is safe for consumption, and is naturally degraded to lysine by proteases, ensuring no harmful residues.
Water Soluble and Effective: ε-Polylysine is highly soluble in water and maintains its antibacterial activity across a wide pH range, enhancing its utility in different environments and formulations.
Epsilon-Polylysine CAS# 28211-04-3
ε-Polylysine is a light yellow powder with high hygroscopicity and a mildly bitter taste. It is a linear polymer made up of lysine. Produced through Streptomyces fermentation, ε-Polylysine exhibits broad-spectrum antibacterial properties. The polymer consists of 25-30 lysine units and is relatively stable to both pH and heat. Its antibacterial effectiveness depends on the degree of polymerization and environmental conditions. The molecular weight of ε-Polylysine ranges from 3600 to 4300, which correlates with its optimal antibacterial activity. Manufactured in Japan, ε-Polylysine has been shown to inhibit bacteria at concentrations as low as 5 ppm, particularly against certain Gram-positive bacteria. It is water-soluble, effective across a wide pH range, and can be broken down into lysine by proteases.
Epsilon-polylysine Chemical Properties
| Melting point | 172 °C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
| Cosmetics Ingredients Functions | SKIN CONDITIONING - MISCELLANEOUS |
| SURFACTANT - EMULSIFYING | |
| HAIR CONDITIONING | |
| InChI | InChI=1/C8H18N2O/c1-3-4-5-6-7(9)8(11)10-2/h7H,3-6,9H2,1-2H3,(H,10,11)/t7-/s3 |
| InChIKey | YLBHPLDJISPYOJ-KPOCXSGKNA-N |
| SMILES | C(NC)(=O)[C@@H](N)CCCCC |&1:4,r| |
Product Application of Epsilon-Polylysine CAS# 28211-04-3
ε-Poly-L-lysine exhibits stronger antimicrobial properties compared to alpha-Poly-L-lysine. Research into its mechanism of action suggests that the antibacterial activity of ε-Poly-L-lysine is largely due to its adsorption to the bacterial cell surface. This macromolecule consists of repeating L-lysyl units connected by 1,6-amide linkages, contributing to its effectiveness in combating microorganisms.
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