Epsilon-polylysine CAS# 28211-04-3
Broad-Spectrum Antibacterial Efficacy: ε-Polylysine exhibits a wide-ranging antibacterial effect, effectively inhibiting various microorganisms, including Gram-positive bacteria, even at low concentrations (as low as 5 ppm).
pH and Heat Stability: The product maintains its antibacterial activity and structural integrity across a broad pH range and under heat exposure, ensuring reliable performance in diverse processing conditions.
Natural and Safe Production: Derived from streptomyces fermentation, ε-Polylysine is a natural linear polymer of lysine, offering a safe and biocompatible option for applications like food preservation.
High Water Solubility and Digestibility: Highly soluble in water and degradable into lysine by proteases, it facilitates easy integration into formulations and ensures metabolic compatibility.
Epsilon-Polylysine (CAS# 28211-04-3)
ε-Polylysine is a light yellow powder characterized by strong hygroscopicity and a slightly bitter taste. As a linear polymer of lysine, it is produced through streptomyces fermentation and exhibits broad-spectrum antibacterial properties. Comprising 25–30 lysine units, ε-polylysine demonstrates relative stability to pH fluctuations and heat exposure. Its antibacterial efficacy is influenced by the degree of polymerization and environmental conditions, with optimal activity observed at a molecular weight range of 3600–4300.
Originating from Japan, ε-polylysine has been shown to inhibit microbial growth at concentrations as low as 5 ppm, particularly against certain Gram-positive bacteria. Additionally, it is highly water-soluble, maintains effectiveness across a wide pH spectrum, and is metabolically degraded into lysine by proteases.
Epsilon-polylysine Chemical Properties
| Melting point | 172 °C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
| Cosmetics Ingredients Functions | SKIN CONDITIONING - MISCELLANEOUS |
| SURFACTANT - EMULSIFYING | |
| HAIR CONDITIONING | |
| InChI | InChI=1/C8H18N2O/c1-3-4-5-6-7(9)8(11)10-2/h7H,3-6,9H2,1-2H3,(H,10,11)/t7-/s3 |
| InChIKey | YLBHPLDJISPYOJ-KPOCXSGKNA-N |
| SMILES | C(NC)(=O)[C@@H](N)CCCCC |&1:4,r| |
Product Application of Epsilon-Polylysine (CAS# 28211-04-3)
ε-Poly-L-lysine exhibits superior antimicrobial efficacy compared to α-Poly-L-lysine. Research indicates that its antibacterial activity is significantly influenced by the adsorption of ε-Poly-L-lysine to bacterial cell surfaces. Structurally, it is a macromolecule formed by repeating L-lysyl units linked through 1,6-amide bonds.
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