Sinsenoside Rb1 CAS#41753-43-9
Major Active Component of American Ginseng – Ginsenoside Rb1 is the principal bioactive constituent of American ginseng, ensuring high functional value.
Proven Anti-Aging Activity – Demonstrated anti-aging effects at both cellular and animal levels, supporting skin and overall vitality.
Enhances Hyaluronic Acid Synthesis – Its key metabolite 20GPPD increases HAS2 expression via ERK and AKT signaling, promoting hyaluronic acid production in human keratinocytes.
Advanced Cellular Signaling Activation – Activates ERK and AKT pathways in a dose-dependent manner, contributing to skin regeneration and anti-aging performance.
Product Description of Ginsenoside Rb1 CAS#41753-43-9
Ginsenoside Rb1 is a glycosylated protopanaxadiol (PPD)–type ginsenoside containing two sugar moieties attached at C-3 and two at C-20, and it represents the principal active component of American ginseng. Research has demonstrated that ginsenoside Rb1 exhibits anti-aging effects at both the cellular and animal levels.
Its main metabolite, 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD), has been shown in vitro to enhance HAS2 expression by activating ERK and AKT phosphorylation pathways in human keratinocytes in a dose-dependent manner.
Parameters
| Melting point | 197.5°C |
| Boiling point | 766.35°C (rough estimate) |
| density | 1.0971 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow |
| pka | 12.85±0.70(Predicted) |
| form | Solid |
| color | Off-White to Pale Beige |
| biological source | plant root (Panax ginseng) |
| Stability: | Hygroscopic |
| InChIKey | GZYPWOGIYAIIPV-VOKNSFSUNA-N |
| LogP | 2.900 (est) |
| CAS DataBase Reference | 41753-43-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn,Xi,T,F |
| Risk Statements | 20/21/22-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-45-36/37-16-7 |
| WGK Germany | 3 |
| RTECS | LZ5856000 |
| HS Code | 29389090 |
| Toxicity | oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76 |
Product Application of Ginsenoside Rb1 CAS#41753-43-9
Ginsenoside Rb1 is a major bioactive constituent of Panax ginseng that enhances neurotransmitter release by regulating synapsin phosphorylation through a cAMP-dependent protein kinase pathway. It has also been reported to exhibit immunostimulatory and anticancer activities.
