Methylprednisolone CAS#83-43-2
Powerful Anti-Inflammatory Effect – Methylprednisolone exhibits strong anti-inflammatory properties, making it highly effective in reducing inflammation associated with various medical conditions.
Immunomodulatory and Anti-Allergic Properties – It helps regulate the immune system and alleviates allergic reactions, supporting treatment of autoimmune and hypersensitivity disorders.
Wide Range of Clinical Applications – This glucocorticoid is used for emergency treatment of critical illnesses and for managing endocrine disorders, rheumatic and collagen diseases, skin conditions, ophthalmic diseases, gastrointestinal disorders, and blood-related illnesses.
Supportive in Complex Therapies – Methylprednisolone is effective in treating leukemia, shock, cerebral edema, neuritis, myelitis, and in preventing chemotherapy-induced vomiting, demonstrating versatility in critical and supportive care.
Products Description of Methylprednisolone CAS#83-43-2
Methylprednisolone (CAS#83-43-2) is a synthetic glucocorticoid with medium potency. It is highly valued in the medical field for its strong anti-inflammatory, immunomodulatory, and anti-allergic effects.
As a glucocorticoid medication, methylprednisolone is used for emergency treatment of critical conditions. It is also applied in managing endocrine disorders, rheumatic and collagen diseases, skin conditions, allergic reactions, ophthalmic disorders, gastrointestinal diseases, blood disorders, leukemia, shock, cerebral edema, neuritis, myelitis, and in preventing chemotherapy-induced vomiting.
Parameters
| Melting point | 228-237°C (dec.) |
| alpha | D20 +83° (dioxane) |
| Boiling point | 423.47°C (rough estimate) |
| density | 1.0868 (rough estimate) |
| refractive index | 82 ° (C=1, Dioxane) |
| storage temp. | 0-6°C |
| solubility | chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow |
| pka | 12.46±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 0.12g/L(25 ºC) |
| Merck | 146111 |
| BRN | 2340300 |
| BCS Class | 2 or 4? |
| InChIKey | VHRSUDSXCMQTMA-PJHHCJLFSA-N |
| CAS DataBase Reference | 83-43-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2) |
| EPA Substance Registry System | Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- (83-43-2) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-36-26 |
| WGK Germany | 2 |
| RTECS | TU4146000 |
| F | 39744 |
| HS Code | 2937290000 |
| Hazardous Substances Data | 83-43-2(Hazardous Substances Data) |
Product Application of Methylprednisolone CAS#83-43-2
Methylprednisolone (CAS#83-43-2), a medium-potency glucocorticoid, exhibits anti-inflammatory, immunosuppressive, and anti-allergic effects. Clinically, it is used for acute flare-ups of rheumatic and immune-related conditions such as rheumatoid arthritis, acute exacerbations of bronchial asthma and other respiratory diseases, as well as ulcerative colitis and other digestive system disorders.
