Dexamethasone CAS#50-02-2
Potent Anti-Inflammatory Effects – Dexamethasone effectively reduces and inhibits inflammation, providing relief from inflammatory symptoms.
Anti-Toxic and Anti-Allergic Properties – The drug exhibits strong anti-toxic and anti-allergic actions, helping to manage allergic reactions and toxic responses.
Synergistic Clinical Use – Dexamethasone is most effective when used in combination with other medications, enhancing the overall therapeutic outcome.
Widely Used in Clinical Practice – It is a commonly applied drug in medical settings, trusted for its reliable ability to manage inflammatory and allergic manifestations.
Products Description of Dexamethasone CAS#50-02-2
Dexamethasone is a widely used drug in clinical practice, frequently administered alongside other medications. It possesses anti-inflammatory, anti-toxic, and anti-allergic properties. However, it does not treat the underlying disease and only serves to reduce or suppress the symptoms of inflammation. Therefore, careful consideration is required during clinical use. It is generally not used alone and is most effective when combined with other drugs.
Parameters
| Melting point | 262-264 °C (lit.) |
| alpha | 75 º (c=1, dioxane) |
| Boiling point | 568.2±50.0 °C(Predicted) |
| density | 1.1283 (estimate) |
| refractive index | 76 ° (C=1, Dioxane) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 mg/mL |
| form | powder |
| pka | 12.13±0.70(Predicted) |
| color | off-white |
| biological source | synthetic (organic) |
| Water Solubility | 10 mg/100 mL (25 ºC) |
| Sensitive | Light Sensitive |
| Merck | 142943 |
| BRN | 2066651 |
| BCS Class | 1 (CLogP), 3 (LogP) |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. |
| InChIKey | UREBDLICKHMUKA-CXSFZGCWSA-N |
| CAS DataBase Reference | 50-02-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) |
| EPA Substance Registry System | Dexamethasone (50-02-2) |
Safety Information
| Hazard Codes | Xi,Xn,T,F |
| Risk Statements | 43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-36-26-22-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | TU3980000 |
| TSCA | Yes |
| HS Code | 29372210 |
| Hazardous Substances Data | 50-02-2(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: > 3gm/kg |
Product Application of Dexamethasone CAS#50-02-2
Dexamethasone (dexamethasone sodium phosphate EP impurity A) is a glucocorticoid widely used for its anti-inflammatory properties. It regulates the survival, growth, and differentiation of T cells and inhibits the induction of nitric oxide synthase.
This drug is primarily applied for anti-inflammatory and anti-allergic purposes and is suitable for treating rheumatoid arthritis and other collagen-related diseases.
