Doxycycline hydrochloride CAS#10592-13-9
Broad-Spectrum Antibacterial Activity – Doxycycline hydrochloride is effective against both Gram-positive cocci and Gram-negative bacilli, making it suitable for a wide range of bacterial infections.
High Antibacterial Potency – Its antibacterial effect is approximately 10 times stronger than tetracycline, providing enhanced therapeutic performance.
Effective Against Resistant Strains – It remains active against tetracycline-resistant bacteria, offering reliable efficacy where conventional tetracyclines may fail.
Wide Clinical Applications – Commonly used for respiratory tract infections, chronic bronchitis, pneumonia, urinary tract infections, typhoid fever, skin macules, and mycoplasma pneumonia.
Products Description of Doxycycline Hydrochloride CAS#10592-13-9
Doxycycline hydrochloride is a light blue to yellow crystalline powder that is odorless, bitter, and hygroscopic. It is readily soluble in water and methanol, and slightly soluble in ethanol and acetone. This product features a broad antibacterial spectrum, showing effectiveness against both Gram-positive cocci and Gram-negative bacilli. Its antibacterial potency is approximately 10 times stronger than tetracycline, while still maintaining activity against tetracycline-resistant bacteria. It is mainly used for respiratory tract infections, chronic bronchitis, pneumonia, and urinary tract infections, and can also be applied in the treatment of macules, typhoid fever, and mycoplasma pneumonia.
Parameters
| Melting point | 195-201℃ |
| Fp | 87℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 50 mg/mL, clear, yellow-green |
| form | powder |
| color | yellow |
| biological source | synthetic |
| Water Solubility | Soluble in water. |
| BCS Class | 1 |
| InChIKey | RUYHIJHUVHIMIR-PGTYNCOMNA-N |
| SMILES | O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r| |
| CAS DataBase Reference | 10592-13-9(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 3 |
| F | 8 |
| HS Code | 29413000 |
Product Application of Doxycycline Hydrochloride CAS#10592-13-9
The antibacterial spectrum of this product is generally similar to that of tetracycline and oxytetracycline, while its antibacterial activity both in vivo and in vitro is stronger than tetracycline. Microorganisms show close cross-resistance between this product and tetracycline, oxytetracycline, and related compounds. It is well absorbed after oral administration.
It is mainly used for the treatment of upper respiratory tract infections, tonsillitis, biliary tract infections, lymphadenitis, cellulitis, and chronic bronchitis in elderly patients caused by sensitive Gram-positive and Gram-negative bacteria. In addition, it is also used for typhus, parasitic diseases, mycoplasma pneumonia, cholera, and for the prevention of malignant malaria and leptospira infection.
