Diethylene glycol CAS#111-46-6
Excellent Solvent Properties : Diethylene glycol dissolves dyes, resins, oils, nitrocellulose, and many organic compounds, making it highly versatile in chemical and textile applications.
Low Volatility and Hygroscopicity : Its low volatility and strong moisture-absorbing ability allow it to function effectively as a softening agent for tobacco, paper, artificial sponges, adhesives, and casein.
Wide Industrial Applications : Used in lubricants, reducing oils, dry cleaning soaps, printing inks, steam-set inks, and non-grain wood stains, as well as a conditioning agent for wool, rayon, and cotton.
Gas Dehydration Capability : Effective in natural gas treatment when combined with monoethanolamine, removing moisture, hydrogen sulfide, and carbon dioxide.
Diethylene Glycol CAS#111-46-6
Diethylene glycol is a clear, colorless, odorless, and stable oily liquid. It is slightly viscous, noncorrosive, and nonvolatile. Due to the presence of both ether and alcohol groups, diethylene glycol exhibits the chemical properties of primary alcohols and ethers. Its boiling point is significantly higher than that of ethylene glycol, and it has stronger solvent capabilities.
Diethylene glycol is miscible with water, ethers, lower aliphatic alcohols, aldehydes, and ketones, and is partially soluble in benzene, carbon tetrachloride, monochlorobenzene, orthodichlorobenzene, and toluene. It can dissolve numerous dyes, resins, oils, nitrocellulose, and various organic compounds. Its solvent strength, low volatility, and hygroscopic nature make it suitable for use in industrial lubricants, reducing oils, dry cleaning soaps, printing inks, steam-set inks, and non-grain wood stains.
In the textile industry, diethylene glycol is employed as a conditioning agent for wool, rayon, and cotton. As a solvent for dyes, it serves as a valuable aid in dyeing and printing processes. Its high hygroscopicity also makes it an effective softening agent for tobacco, paper, synthetic sponges, adhesives, and casein.
Additionally, diethylene glycol is particularly useful in natural gas dehydration. When combined with monoethanolamine, it efficiently removes moisture, hydrogen sulfide, and carbon dioxide from natural gas.
Diethylene glycol Chemical Properties
Melting point | −10 °C(lit.) |
Boiling point | 245 °C(lit.) |
density | 1.118 g/mL at 25 °C(lit.) |
vapor density | 2.14 (vs air) |
vapor pressure | 0.01 mm Hg ( 20 °C) |
refractive index | n20/D 1.447(lit.) |
Fp | 143 °C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | H2O: 50 mg/mL at 20 °C, clear, colorless |
pka | 14.03±0.10(Predicted) |
form | Oily Liquid |
color | colorless |
Relative polarity | 0.713 |
PH | 5.5-7.0 (25℃, 50mg/mL in H2O) |
Odor | Practically odorless. |
explosive limit | 2-12.3% |
Water Solubility | SOLUBLE |
FreezingPoint | -10.45℃ |
Sensitive | Hygroscopic |
λmax | λ: 260 nm Amax: ≤0.02 |
Merck | 14,3119 |
BRN | 969209 |
Dielectric constant | 31.7(20℃) |
Stability: | Hygroscopic |
InChIKey | MTHSVFCYNBDYFN-UHFFFAOYSA-N |
LogP | -1.98 at 20℃ |
CAS DataBase Reference | 111-46-6(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanol, 2,2'-oxybis-(111-46-6) |
EPA Substance Registry System | Diethylene glycol (111-46-6) |
Safety Information
Hazard Codes | Xn,T,Xi |
Risk Statements | 22 |
Safety Statements | 46 |
WGK Germany | 1 |
RTECS | ID5950000 |
F | 10 |
Autoignition Temperature | 442 °F |
Hazard Note | Toxic/Irritant |
TSCA | Yes |
HS Code | 29094100 |
Hazardous Substances Data | 111-46-6(Hazardous Substances Data) |
Toxicity | LD50 in rats, guinea pigs (g/kg): 20.76, 13.21 orally (Smyth) |
Product Usage
Propanols are widely used as solvents in coatings, antifreeze formulations, and household and personal care products. They also serve as chemical intermediates in the production of esters, amines, and other organic derivatives. Specifically, 1-propanol is commonly employed as a solvent in printing inks, paints, cosmetics, pesticides, cellulose esters, and insecticides.
1-Propanol is also commercially utilized in the manufacture of glycol ethers, which feature dual functionality, offering high solvency, chemical stability, and compatibility with water.



