Meglumine CAS#6284-40-8
Ideal for Pharmaceutical Quality Control: The product is suitable for use as a pharmaceutical secondary standard in quality control applications.
Cost-Effective Alternative: It provides laboratories and manufacturers with a convenient and economical alternative to preparing in-house working standards.
Widely Used Pharmaceutical Excipient: Meglumine is broadly applied as an excipient in pharmaceutical formulations, supporting formulation stability and performance.
Glucose-Derived Compound with Reliable Properties: As a glucose-derived secondary amine, meglumine offers dependable chemical characteristics for pharmaceutical applications.
Meglumine Chemical Properties
| Melting point | 129-131.5 °C (lit.) |
| alpha | -16.5 º (c=10, H2O, on dry sub) |
| Boiling point | 331.88°C (rough estimate) |
| bulk density | 300kg/m3 |
| density | 1.2669 (rough estimate) |
| refractive index | -16.5 ° (C=2, H2O) |
| RTECS | LZ4295770 |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| pka | pKa 9.39(H2O,t =30.0,I=0.05N2)(Approximate) |
| form | Crystalline Powder |
| color | White to almost white |
| PH | 11 (10g/l, H2O, 20℃) |
| biological source | synthetic (organic) |
| Optical Rotation | [α]20/D 16.5±0.5°, c = 2% in H2O |
| Water Solubility | 100 g/100 mL (25 ºC) |
| Sensitive | Air Sensitive & Hygroscopic |
| Merck | 146078 |
| BRN | 385906 |
| Major Application | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions | HAIR CONDITIONING |
| InChI | 1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1 |
| InChIKey | MBBZMMPHUWSWHV-VZFHVOOUSA-N |
| SMILES | CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO |
| LogP | -3.370 (est) |
| NIST Chemistry Reference | N-methylglucamine(6284-40-8) |
| EPA Substance Registry System | Meglumine (6284-40-8) |
Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| F | 37917 |
| Autoignition Temperature | ~662 °F |
| TSCA | TSCA listed |
| HS Code | 29221980 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
Product Application of Meglumine CAS#6284-40-8
N-Methyl-D-glucamine is commonly used together with iodinated organic compounds in contrast media, such as diatrizoate meglumine and iodipamide meglumine. It is also applied in ion-exchange resins for the selective chelation of boron ions.
In addition, it serves as an excipient in pharmaceutical formulations, as well as in cosmetics and X-ray contrast media. It is further utilized in the synthesis of surfactants, pharmaceuticals, and dyes.
