Sodium carboxyl methylstarch CAS#9063-38-1

Excellent Flowability: Presented as a free-flowing powder, ensuring easy handling, processing, and uniform mixing in formulations.
High Hygroscopicity: Strong moisture absorption capability, supporting rapid interaction with aqueous environments.
Superior Swelling Capacity: Exhibits significant swelling upon contact with water, enhancing its functional performance in applications such as disintegration.
Consistent Particle Structure: Features well-defined granule morphology with uniform size distribution, contributing to stable and reliable product performance.

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Product Details

Product Description: Sodium Carboxymethyl Starch (CAS# 9063-38-1)

Sodium starch glycolate is a white or nearly white, free-flowing powder with strong hygroscopic properties. According to PhEur 6.0, microscopic examination shows that it consists of irregularly shaped granules, including ovoid or pear-shaped particles ranging from 30–100 μm, as well as rounded granules of 10–35 μm. Occasionally, compound granules composed of 2–4 units may be observed.

The granules feature an eccentric hilum with clearly visible concentric striations. Under crossed Nicol prisms, a distinct black cross can be seen intersecting at the hilum, and small crystals are present on the granule surfaces. When in contact with water, the granules exhibit significant swelling behavior.

Sodium carboxyl methylstarch CAS#9063-38-1

Sodium carboxyl methylstarch Chemical Properties

Melting point	>210°C (dec.)
storage temp.	Inert atmosphere,Room Temperature
solubility	Practically insoluble in methylene chloride. It gives a translucent suspension in water.
form	Solid
color	White to Off-White
Major Application	pharmaceutical (small molecule)
Cosmetics Ingredients Functions	EMULSION STABILISING
	BINDING
	VISCOSITY CONTROLLING
	FILM FORMING
CAS DataBase Reference	9063-38-1
EPA Substance Registry System	Starch, carboxymethyl ether, sodium salt (9063-38-1)
WGK Germany	1
TSCA	TSCA listed
HS Code	3505100092
Storage Class	11 - Combustible Solids

Sodium carboxyl methylstarch CAS#9063-38-1

Product Application: Sodium Carboxymethyl Starch (CAS# 9063-38-1)

Sodium starch glycolate is widely utilized in oral pharmaceutical formulations as a disintegrant for capsules and tablets. It is suitable for use in both direct compression and wet granulation processes. The typical usage level ranges from 2% to 8%, with an optimal concentration around 4%, although in many formulations 2% is sufficient. Its disintegration mechanism is based on rapid water absorption followed by significant swelling.

Unlike many disintegrants, its performance is not adversely affected by hydrophobic excipients such as lubricants. Additionally, increasing tablet compression pressure does not significantly impact its disintegration efficiency. Sodium starch glycolate has also been studied for use as a suspending agent in pharmaceutical formulations.

Sodium carboxyl methylstarch CAS#9063-38-1