Scabertopin CAS#185213-52-9

Natural Plant-Derived Compound: Extracted from Elephantopus scaber Linn., providing a naturally sourced bioactive ingredient.
Significant Antitumor Activity: Demonstrates notable in vitro antitumor effects, supporting pharmaceutical and oncology research.
Well-Defined Chemical Structure: Features a clear molecular formula and molecular weight for accurate research and formulation applications.
Valuable Research Chemical: Widely suitable for scientific studies involving natural products and bioactive compounds.

Contact Now E-Mail Telephone WhatsApp

Product Details

Scabertopin CAS#185213-52-9

Scabertopin (CAS# 185213-52-9) is a sesquiterpene lactone natural compound, with molecular formula C20H22O6 and a molecular weight of 358.39. Extracted from Elephantopus scaber Linn., it exhibits significant antitumor activity in vitro. It is commonly used as a research chemical,

Scabertopin CAS#185213-52-9

Scabertopin Chemical Properties

Boiling point	592.7±50.0 °C(Predicted)
density	1.24±0.1 g/cm3(Predicted)
form	Solid
color	White to light yellow
InChI	InChI=1S/C20H22O6/c1-5-11(3)18(21)25-16-9-13-8-14(24-20(13)23)6-10(2)7-15-17(16)12(4)19(22)26-15/h5,7-8,14-17H,4,6,9H2,1-3H3/b10-7+,11-5-/t14-,15+,16-,17-/m0/s1
InChIKey	FTPHYXGWMIZVMP-RZYABJHASA-N
SMILES	C(O[C@H]1CC2=C[C@]([H])(CC(C)=C[C@@]3([H])OC(=O)C(=C)[C@@]31[H])OC2=O)(=O)/C(/C)=C\C \|t:10\|

Product Application of Scabertopin CAS#185213-52-9

Elephantoplastin has demonstrated notable antitumor activity by inhibiting the proliferation of various tumor cell types. Topical administration of its active component (100 mg/kg) has been shown to delay papilloma formation, reduce the average number of papillomas, and lower the average body weight of papilloma-bearing mice. Intraperitoneal injection of the active component also exhibits significant inhibitory effects on soft tissue tumors induced by subcutaneous injection of 20-methylcholanthrene (20-MCA). Compared with the 20-MCA-induced control group, Elephantoplastin extract reduces both the incidence of sarcomas and tumor size. In addition, intraperitoneal treatment significantly suppresses the growth of subcutaneously transplanted Dalton lymphoma ascites (DLA) cells and Ehrlich ascites carcinoma (EAC) solid tumors, while prolonging the survival time of tumor-bearing mice.

Scabertopin CAS#185213-52-9