Rotenone CAS#83-79-4
Natural Plant-Derived Ingredient: Rotenone is primarily extracted from the tuber roots of Derris elliptica and other botanical sources, offering a naturally derived active compound.
Effective Contact and Stomach Action: The product provides both contact and stomach poisoning effects against arthropods, delivering efficient pest control performance.
Fast Knockdown Performance: Rotenone exhibits rapid knockdown activity by interfering with mitochondrial respiratory enzymes and disrupting essential biochemical processes.
Multiple Botanical Sources Available: In addition to Derris elliptica, rotenone can also be sourced from Derris mallaccensis, Lonchocarpus utilis, and Lonchocarpus uruca, ensuring stable and diverse raw material supply.
Rotenone CAS#83-79-4
Rotenone is mainly obtained from the tuber roots of Derris elliptica, and can also be extracted from the roots of Derris mallaccensis, Lonchocarpus utilis, and Lonchocarpus uruca. It acts as both a contact and stomach poison against arthropods. Its rapid knockdown effect is associated with reducing the availability of nicotinamide adenine dinucleotide (NAD) as a cofactor in key biochemical pathways, including the Krebs cycle, which results in the inhibition of mitochondrial respiratory enzymes.
Rotenone Chemical Properties
| Melting point | 159-164 °C (lit.) |
| alpha | -115 º (C=1.4 IN CHLOROFORM) |
| Boiling point | 210-220 °C/0.5 mmHg (lit.) |
| density | 1.1917 (rough estimate) |
| refractive index | 1.4593 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | insoluble in EtOH; insoluble in H2O; ≥77.6 mg/mL in DMSO |
| Water Solubility | 15 mg l-1 (100 °C) |
| form | White to off-white solid |
| color | White to Light yellow to Light orange |
| Merck | 148271 |
| BRN | 6773081 |
| Stability: | Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, especially in the presence of alkalies. |
| InChI | 1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1 |
| InChIKey | JUVIOZPCNVVQFO-HBGVWJBISA-N |
| SMILES | COc1cc2OCC3Oc4c5C[C@@H](Oc5ccc4C(=O)C3c2cc1OC)C(C)=C |
| NIST Chemistry Reference | Rotenone(83-79-4) |
| EPA Substance Registry System | Rotenone (83-79-4) |
Safety Information
| Hazard Codes | T,N |
| Risk Statements | 25-36/37/38-50/53 |
| Safety Statements | 22-24/25-36-45-60-61 |
| OEB | B |
| OEL | TWA: 5 mg/m3 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | DJ2800000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29329990 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 |
| very toxic hazardous materials | |
| Hazard Classifications | Acute Tox. 1 Inhalation |
| Acute Tox. 2 Oral | |
| Aquatic Acute 1 | |
| Aquatic Chronic 1 | |
| Eye Irrit. 2 | |
| Skin Irrit. 2 | |
| STOT SE 3 | |
| Hazardous Substances Data | 83-79-4(Hazardous Substances Data) |
| Toxicity | LD50 i.p. in mice: 2.8 mg/kg (Fukami); in rats (mg/kg): 132 orally; 6 i.v. (Soloway) |
| IDLA | 2,500 mg/m3 |
Product Application of Rotenone CAS#83-79-4
Rotenone is a broad-spectrum insecticide naturally found in the seeds and stems of several plant species. First registered in 1947, it is currently used primarily as a piscicide for fish control applications in the United States (U.S. EPA, 2007). In 2006, all livestock, residential, homeowner, domestic pet, and other non-piscicide uses were voluntarily canceled by registrants. Today, its primary applications include fish management programs aimed at eliminating nonnative fish species from lakes, ponds, and streams, as well as use in catfish aquaculture before pond stocking to remove unwanted fish species (U.S. EPA, 2006d).
Historically, rotenone was used by indigenous communities to immobilize fish for harvesting and consumption. In some countries outside the United States, it continues to be utilized for insect control in fruit and vegetable cultivation, as well as for managing fire ants and mosquito larvae in pond water (HSDB, 2012a).
