Levofloxacin hydrochloride CAS#177325-13-2
Enhanced Antibacterial Potency: As the levorotatory form of ofloxacin, levofloxacin hydrochloride provides approximately twice the antibacterial activity of ofloxacin.
Broad-Spectrum Antibacterial Coverage: It offers a wide antibacterial spectrum, making it effective against a broad range of susceptible bacterial strains.
Strong Bactericidal Performance: The product delivers powerful antibacterial effects, supporting reliable therapeutic efficacy in pharmaceutical applications.
Targeted DNA Replication Inhibition: It works by inhibiting bacterial DNA gyrase (topoisomerase II), effectively blocking bacterial DNA replication and suppressing microbial growth.
Product Description of Levofloxacin Hydrochloride CAS#177325-13-2
Levofloxacin hydrochloride is the levorotatory form of ofloxacin, with approximately twice the antibacterial activity of ofloxacin. Its primary mechanism of action is the inhibition of bacterial DNA gyrase (topoisomerase II), which interferes with bacterial DNA replication and effectively suppresses microbial growth.
The product is characterized by a broad antibacterial spectrum and strong antibacterial efficacy, making it widely applicable in pharmaceutical and anti-infective formulations.
Parameters
Levofloxacin hydrochloride Chemical Properties
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
| form | Solid |
| color | White to Pale Beige |
| HS Code | 29349990 |
| Levofloxacin hydrochloride Usage And Synthesis | |
| Uses | Levofloxacin Hydrochloride is a fluoroquinolone broad spectrum antibiotic. It is an inhibitor of two enzymes, DNA gyrase and topoisomerase IV. |
| IC 50 | TOPO IV |
Product Application of Levofloxacin Hydrochloride CAS#177325-13-2
Levofloxacin hydrochloride is suitable for the treatment of mild to moderate infections caused by susceptible bacteria, and it is also applicable to certain severe infections depending on clinical requirements.
Indications: This product is used for a wide range of infections caused by sensitive bacterial strains, including:
Respiratory tract infections: acute bronchitis, chronic bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchiolitis, bronchiectasis with infection, pneumonia, pharyngitis, tonsillitis, and peritonsillar abscess.
Urinary tract infections: pyelonephritis, complicated urinary tract infections, and related conditions.
Reproductive system infections: prostatitis, epididymitis, uterine cavity infection, adnexitis, and pelvic inflammatory disease. When anaerobic infection is suspected, it may be used in combination with metronidazole.
Skin and soft tissue infections: impetigo, cellulitis, lymphangitis (adenitis), subcutaneous abscess, and perianal abscess.
Intestinal infections: bacillary dysentery, infectious enteritis, Salmonella enteritis, typhoid fever, and paratyphoid fever.
Other infections: wound and trauma-related infections.
