Methanesulfonic acid CAS#75-75-2
Environmentally Friendly Profile : Classified as a "green acid" due to lower toxicity and reduced corrosiveness compared to traditional mineral acids, minimizing environmental impact.
Biodegradability : Undergoes natural degradation into CO₂ and sulfate, ensuring sustainability and compliance with ecological standards.
Versatile Electrolyte Applications : Serves as a model aqueous electrolyte for electrochemical processes, enabling efficient and stable performance in energy storage and conversion systems.
Unique Chemical Structure & Functionality : Acts as an alkanesulfonic acid with a methyl group linked to the sulfo functionality, and serves as an Escherichia coli metabolite, broadening its utility in biological and chemical contexts.
Products Description of Methanesulfonic Acid CAS#75-75-2
Methanesulfonic acid (CH₃SO₃H, MSA) is a strong organic acid. It is formed in the atmosphere through the chemical oxidation of dimethyl sulfide in large quantities and can undergo biodegradation to produce CO₂ and sulfate. MSA is regarded as a green acid due to its lower toxicity and corrosiveness compared to traditional mineral acids. Its aqueous solutions are often used as model electrolytes in electrochemical processes.
Chemically, methanesulfonic acid is an alkanesulfonic acid in which a methyl group is directly attached to the sulfonic functionality. It functions as a metabolite of Escherichia coli, is classified as a one-carbon compound, and serves as the conjugate acid of methanesulfonate.
| Melting point | 17-19 °C (lit.) |
| Boiling point | 167 °C/10 mmHg (lit.) |
| density | 1.475-1.485 g/mL at 20 °C 1.481 g/mL at 25 °C (lit.) |
| vapor density | 3.3 (vs air) |
| vapor pressure | 1 mm Hg ( 20 °C) |
| refractive index | n20/D 1.429(lit.) |
| Fp | >230 °F |
| storage temp. | 2-8°C |
| solubility | water: soluble1,000 g/L at 20°C |
| form | Solution |
| pka | -2.6(at 25℃) |
| Specific Gravity | 1.48 (18/4℃) |
| color | brown |
| biological source | synthetic |
| Water Solubility | Miscible with water. Slightly miscible with benzene and toluene. Immiscible with paraffins. |
| λmax | λ: 240-320 nm Amax: <0.4 |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 145,954 |
| BRN | 1446024 |
| Stability: | Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting). |
| InChIKey | AFVFQIVMOAPDHO-UHFFFAOYSA-N |
| CAS DataBase | 75-75-2(CAS DataBase Reference) |
| Reference | |
| NIST Chemistry | CH3SO3H(75-75-2) |
| Reference | |
| EPA Substance | Methanesulfonic acid (75-75-2) |
| Registry System | |
| Hazard Codes | C |
| Risk Statements | 34-22-21/22-35 |
| Safety | 26-36-45-1/2-36/37/39 |
| Statements | |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 1 |
| RTECS | PB1140000 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29041000 |
| Hazardous | 75-75-2(Hazardous Substances Data) |
| Substances Data | |
| Toxicity | LD50 orally in Rabbit: 649 mg/kg LD50 dermal Rabbit 200 - 2000 mg/kg |
Product Application of Methanesulfonic Acid CAS#75-75-2
Methanesulfonic acid is widely used as a catalyst in organic reactions such as esterification, alkylation, and condensation due to its non-volatile nature and good solubility in organic solvents. It is employed in the synthesis of starch esters, wax oxidate esters, benzoic acid esters, phenolic esters, and various alkyl esters. In the presence of the polar solvent tetrahydrofuran, it reacts with sodium borohydride to produce the borane-tetrahydrofuran complex.
Its high purity and absence of chloride make it valuable in battery applications. In the pharmaceutical industry, MSA is used for producing active pharmaceutical ingredients like telmisartan and eprosartan. It is also applied in ion chromatography and serves as a source of carbon and energy for certain gram-negative methylotrophic bacteria. Additionally, it plays a role in peptide deprotection processes.
