Phthalic anhydride CAS#85-44-9
Important Industrial Chemical: Phthalic anhydride is a widely used industrial raw material with significant importance in chemical manufacturing.
Key Intermediate for Plasticizer Production: It serves as a primary feedstock for the large-scale production of plasticizers used in various plastic applications.
Versatile Chemical Building Block: As the anhydride of phthalic acid, it is an essential intermediate for the synthesis of numerous chemical products and derivatives.
Suitable for Large-Scale Manufacturing: Its established industrial use and consistent properties make it well-suited for commercial-scale production processes.
Phthalic Anhydride CAS#85-44-9
Phthalic anhydride is an organic compound with the molecular formula C₆H₄(CO)₂O. It is the anhydride form of phthalic acid. This colorless solid is an important industrial chemical, particularly widely used in the large-scale production of plasticizers for plastics.
Phthalic anhydride Chemical Properties
| Melting point | 131-134 °C(lit.) |
| Boiling point | 284 °C(lit.) |
| bulk density | 500-700kg/m3 |
| density | 1,53 g/cm3 |
| vapor density | 5.1 (vs air) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| refractive index | 1.4500 (estimate) |
| Fp | 152 °C |
| storage temp. | Store below +30°C. |
| solubility | 6g/l (slow decomposition) |
| form | Flaky Crystals |
| pka | 2.97[at 20 ℃] |
| color | White |
| Odor | Characteristic choking odor |
| PH | 2 (6g/l, H2O, 20℃) |
| PH Range | 2 at 6 g/l at 20 °C |
| explosive limit | 1.7-10.5%(V) |
| Water Solubility | 6 g/L (20 ºC) |
| Sensitive | Moisture Sensitive |
| Merck | 147372 |
| BRN | 118515 |
| Henry's Law Constant | 6.29 at 20 °C (approximate - calculated from water solubility and vapor pressure) |
| Exposure limits | NIOSH REL: TWA 6 mg/m3 (1 ppm), IDLH 60 mg/m3; OSHA PEL: TWA 12 mg/m3 (2 ppm); ACGIH TLV: TWA 1 ppm (adopted). |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, moisture, strong acids. Dust may form an explosive mixture with air. |
| Cosmetics Ingredients Functions | NOT REPORTED |
| InChI | 1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H |
| InChIKey | LGRFSURHDFAFJT-UHFFFAOYSA-N |
| SMILES | O=C1OC(=O)c2ccccc12 |
| LogP | 2.07 at 20℃ |
| CAS DataBase Reference | 85-44-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Phthalic anhydride(85-44-9) |
| EPA Substance Registry System | Phthalic anhydride (85-44-9) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41-42/43 |
| Safety Statements | 23-24/25-26-37/39-46-22 |
| RIDADR | 2214 |
| OEB | B |
| OEL | TWA: 6 mg/m3 (1 ppm) |
| WGK Germany | 1 |
| RTECS | TI3150000 |
| F | 46316 |
| Autoignition Temperature | 580 °C |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29173500 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Eye Dam. 1 | |
| Resp. Sens. 1 | |
| Skin Irrit. 2 | |
| Skin Sens. 1 | |
| STOT SE 3 | |
| Hazardous Substances Data | 85-44-9(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 1530 mg/kg LD50 dermal Rabbit > 3160 mg/kg |
| IDLA | 60 mg/m3 |
Product Application of Phthalic Anhydride CAS#85-44-9
Phthalic anhydride reacts with cellulose acetate to produce cellulose acetate phthalate (CAP), a widely used enteric coating excipient that has also demonstrated antiviral activity. Phthalic anhydride is also identified as a degradation product of CAP.
