4-Fluorobenzaldehyde CAS#459-57-4
Versatile Reactivity for Organic Synthesis ： Possesses typical aldehyde group properties enabling oxidation, reduction, and condensation reactions, making it a valuable intermediate in diverse chemical transformations.
Unique Fluorine-Containing Reactive Site ： Incorporates fluorine atoms that introduce special reactivity, serving as a distinctive functional group for targeted organic synthesis applications.
Colorless to Pale Yellow Liquid Form ： Maintains a clear appearance with minimal impurities, facilitating ease of handling and integration into reaction processes.
Characteristic Aromatic Odor ： Emits a recognizable scent that can aid in identification and quality control during manufacturing or laboratory use.
4-Fluorobenzaldehyde CAS#459-57-4
4-Fluorobenzaldehyde (CAS#459-57-4) is a key intermediate in organic synthesis. It typically exists as a colorless to pale yellow liquid, emitting a distinctive aromatic odor. As an aldehyde compound, it exhibits standard reactivity such as oxidation, reduction, and condensation. The incorporation of fluorine atoms further enhances its unique chemical properties, enabling it to act as a specialized reactive site in synthetic applications.
Parameters
| Melting point | -10 °C (lit.) |
| Boiling point | 181 °C/758 mmHg (lit.) |
| density | 1.157 g/mL at 25 °C (lit.) |
| vapor pressure | 19 hPa (70 °C) |
| refractive index | n20/D 1.521(lit.) |
| Fp | 134 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform, Methanol |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.157 |
| Water Solubility | IMMISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 385857 |
| Stability: | Air Sensitive |
| InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
| CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
| EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
Safety Information
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39-36/37/39-27 |
| RIDADR | UN 1989 3/PG 3 |
| WGK Germany | 2 |
| F | 9月23日 |
| Hazard Note | Flammable |
| TSCA | T |
| HazardClass | 3.2 |
| PackingGroup | III |
| HS Code | 29130000 |
Product Application of 4-Fluorobenzaldehyde (CAS#459-57-4)
4-Fluorobenzaldehyde is a fluorinated benzaldehyde derivative with demonstrated inhibitory activity against mushroom tyrosinase. It serves as a key intermediate in synthesizing pyrazolopyridine derivatives, which function as mitogen-activated protein kinase (MAPK) inhibitors. Additionally, this compound plays a critical role as a synthetic building block in the preparation of pharmaceutical agents.
