Tetrahydrothiophene CAS#110-01-0

  • Excellent Odor Detection Performance: Tetrahydrothiophene can be detected in air at concentrations as low as 0.01 ppm, providing highly effective leak-warning performance.

  • Stable and Long-Lasting Odorant: It offers good chemical stability and is not easily lost by volatilization, ensuring reliable long-term odorization in gas systems.

  • Non-Corrosive to Equipment and Pipelines: The product is non-corrosive to gas equipment, transportation pipeline gaskets, and related materials, helping protect infrastructure integrity.

  • No Olfactory Fatigue Risk: It does not cause habitual desensitization of the human sense of smell, making it a safer and more dependable odorant for LPG and natural gas applications.


Product Details

Product Description of Tetrahydrothiophene CAS#110-01-0

Tetrahydrothiophene is a cyclic thioalkane and the saturated analog of thiophene. It appears as a colorless, transparent, volatile liquid, insoluble in water but miscible with ethanol, ether, benzene, and acetone.

The product has a strong, distinctive odor and offers excellent stability with low volatilization loss. Its odor can be detected in air at concentrations as low as 0.01 ppm, making it highly effective for leak detection applications.

It is non-corrosive to gas equipment, transportation pipeline gaskets, and related materials, and does not cause olfactory desensitization during repeated exposure. For these reasons, tetrahydrothiophene is widely used as an odorant for LPG and natural gas systems, serving as an advanced alternative to traditional agents such as ethyl mercaptan.


Tetrahydrothiophene Chemical Properties

Melting point -96 °C (lit.)
Boiling point 119 °C (lit.)
density 1 g/mL at 25 °C (lit.)
vapor pressure 18 mm Hg ( 25 °C)
refractive index n20/D 1.504(lit.)
Fp 55 °F
storage temp. Store below +30°C.
solubility immiscible
form liquid
Specific Gravity1.002 (20/4℃)
color Colorless to Almost colorless
OdorSmells of rotting eggs
PH7 (H2O, 20℃)
explosive limit1.1-12.1%(V)
Odor Threshold0.00062ppm
Odor Typesulfurous
Water Solubility immiscible
Merck 149218
BRN 102392
Dielectric constant8.61
Stability:Highly flammable. Vapour-air mixtures explosive in some proportions; note low flash point and fairly wide explosion limit range. Heavier than air, so potentially explosive mixtures may travel considerable distances to source of ignition.
LogP1.8 at 20℃
CAS DataBase Reference110-01-0(CAS DataBase Reference)
NIST Chemistry ReferenceThiophene, tetrahydro-(110-01-0)
EPA Substance Registry SystemTetrahydrothiophene (110-01-0)

Safety Information

Hazard Codes F,Xn
Risk Statements 11-20/21/22-36/38-52/53
Safety Statements 16-23-36/37-61
RIDADR UN 2412 3/PG 2
WGK Germany 2
RTECS XN0370000
Autoignition Temperature202 °C
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29349990
Hazardous Substances Data110-01-0(Hazardous Substances Data)
ToxicityLD50 by inhalation in mice: 26.7 mg/l (Carlucci)

Product Application of Tetrahydrothiophene CAS#110-01-0

Tetrahydrothiophene is widely used as a solvent and fuel gas odorant, particularly in fire safety warning systems for underground mines, where its strong and easily detectable odor supports reliable leak and hazard identification.

In addition to industrial gas applications, tetrahydrothiophene has also been utilized as an organocatalyst in organic synthesis, specifically in the reaction of enynediones with benzoic acid to produce highly substituted furfuryl alcohol benzoates.


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