Furaneol CAS#3658-77-3
Natural Fruit Flavor: Key aroma in strawberries and fruits.
Multi-Source Synthesis: Produced via Maillard reaction or biological pathways.
Skin Health Potential: Inhibits hyperpigmentation by targeting cAMP pathways.
Antimicrobial Properties: Shows promise as a human-safe antimicrobial agent.
Furaneol (CAS#3658-77-3)
Furaneol is a pivotal aroma chemical and a primary flavoring compound naturally occurring in diverse fruits. It can be chemically synthesized through carbohydrates via the Maillard reaction or produced by yeast, bacteria, and plants, where it also exerts physiological effects. Research indicates that furaneol inhibits the phosphorylation of cAMP response element binding protein, suggesting its potential as an effective hyperpigmentation inhibitor. Additionally, it may serve as a promising antimicrobial agent for human applications.
Structurally, furaneol belongs to the furan class, specifically as 2,5-dimethylfuran with oxo and hydroxy groups at positions 3 and 4. It is abundantly found in strawberries and similar fruits.
Furaneol Chemical Properties
Melting point | 73-77 °C(lit.) |
Boiling point | 188 °C |
density | 1.049 g/mL at 25 °C |
vapor pressure | 0.81Pa at 25℃ |
refractive index | n20/D 1.439 |
FEMA | 3174 | 4-HYDROXY-2,5-DIMETHYL-3(2H)-FURANONE |
Fp | >230 °F |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 9.62±0.40(Predicted) |
form | Solid |
color | White |
Odor | at 1.00 % in propylene glycol. sweet cotton candy caramel strawberry sugar |
Odor Type | caramellic |
biological source | synthetic |
Water Solubility | 176g/L at 20℃ |
JECFA Number | 1446 |
BRN | 1281357 |
Stability: | Light Sensitive, Temperature Sensitive |
Cosmetics Ingredients Functions | TONIC |
InChIKey | INAXVXBDKKUCGI-UHFFFAOYSA-N |
LogP | 0.95 at 20℃ |
CAS DataBase Reference | 3658-77-3(CAS DataBase Reference) |
NIST Chemistry Reference | 2,5-Dimethyl-4-hydroxy-3(2h)-furanone(3658-77-3) |
EPA Substance Registry System | 4-Hydroxy-2,5-dimethyl-3(2H)furanone (3658-77-3) |
Safety Information
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 36-24/25 |
WGK Germany | 3 |
RTECS | LU3990000 |
F | 10-23 |
HS Code | 29321900 |
Hazardous Substances Data | 3658-77-3(Hazardous Substances Data) |
Product Application of Furaneol (CAS#3658-77-3)
2,5-Dimethyl-4-hydroxy-3(2H)-furanone, commonly known as furaneol, is a key ingredient in meat essence formulations. Its sweet strawberry-like aroma makes it widely utilized in the flavor and fragrance industry.
