Dihydromyricetin CAS#27200-12-0

Natural Flavonoid Compound: Dihydromyricetin (DHM) is a naturally occurring flavonoid widely found in Asian plant species and traditionally used in herbal medicine.
Potential Hepatoprotective Effects: DHM has demonstrated significant liver-protective properties, particularly in studies related to alcohol-induced and other liver diseases.
Multiple Biological Activities: The compound exhibits antimicrobial, anti-inflammatory, antioxidant, anticancer, and metabolism-regulating activities.
Low Impact on Normal Cells: DHM can mediate cell death with little or minimal adverse effects on normal healthy cells, supporting its research and therapeutic potential.

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Product Details

Dihydromyricetin CAS#27200-12-0

Dihydromyricetin (DHM), also known as ampelopsin, is a naturally occurring flavonoid compound widely found in Asian plant species. One notable source is Hovenia dulcis, which has been used for centuries in traditional Chinese medicine for relieving alcohol intoxication and hangover symptoms. DHM is commonly marketed as a dietary supplement due to its potential to lower blood alcohol levels and its proposed liver-protective properties.

Dihydromyricetin has demonstrated a variety of beneficial biological activities, including antimicrobial, anti-inflammatory, antioxidant, anticancer, and lipid- and glucose-metabolism regulatory effects. It can also mediate cell death while causing little or minimal adverse effects on normal cells. Most importantly, studies have shown that DHM possesses significant hepatoprotective activity, with positive effects observed in alcohol-related and other liver diseases, including acute liver failure research.

Dihydromyricetin CAS#27200-12-0

Dihydromyricetin Chemical Properties

storage temp.	-20°C
solubility	DMSO: ≥5mg/mL (warmed)
Melting point	239-241 °C
pKa	7.38±0.60(Predicted)
Boiling point	780.7±60.0 °C(Predicted)
density	1.808±0.06 g/cm3(Predicted)
form	powder
color	white to beige
Stability:	Hygroscopic
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChI	InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey	KJXSIXMJHKAJOD-LSDHHAIUSA-N
SMILES	[C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP	1.230 (est)
CAS DataBase Reference	27200-12-0
Safety Statements	24/25
WGK Germany	3
HS Code	29329990
Storage Class	11 - Combustible Solids

Dihydromyricetin CAS#27200-12-0

Product Application of Dihydromyricetin CAS#27200-12-0

Dihydromyricetin can be used as a novel anti-alcoholism agent and has been clinically applied for the treatment of hangovers, fever, parasitic infections, and liver-related diseases. It is also currently under clinical investigation for its potential effects on glycemic control, insulin sensitivity, and insulin secretion in patients with type 2 diabetes.

Dihydromyricetin CAS#27200-12-0