N-Methylaniline CAS#100-61-8
High Chemical Stability: Exhibits low reactivity under normal conditions (NFPA Reactivity Rating: 0), making it suitable for a variety of chemical processing and synthesis applications.
Convenient Liquid Form: Available as a liquid at room temperature, allowing for easy handling, transfer, and incorporation into manufacturing processes.
Low Volatility Characteristics: Features a relatively low vapor pressure (0.3 mmHg at 20°C), which helps reduce evaporation losses during storage and use.
Versatile Industrial Intermediate: Widely utilized as an important intermediate in the production of dyes, pharmaceuticals, agrochemicals, rubber chemicals, and other specialty chemicals.
N-Methylaniline CAS#100-61-8
N-Methylaniline is a yellow to light brown oily liquid characterized by a slight ammonia-like odor. It may develop a reddish-brown appearance upon standing. The compound has a molecular weight of 107.17, a specific gravity of 0.99, a boiling point of 195.6°C, a melting point of -57.2°C, a vapor pressure of 0.3 mmHg at 20°C, and a flash point of 79.4°C. Based on the NFPA 704 classification system, its ratings are Health 2, Flammability 2, and Reactivity 0. It is practically insoluble in water.
N-Methylaniline Chemical Properties
| Melting point | -57 °C (lit.) |
| Boiling point | 196 °C (lit.) |
| density | 0.989 g/mL at 25 °C (lit.) |
| vapor pressure | 0.5 hPa (20 °C) |
| refractive index | n20/D 1.571(lit.) |
| Fp | 174 °F |
| storage temp. | Store below +30°C. |
| solubility | water: slightly soluble30g/L |
| form | Liquid |
| pka | 4.84(at 25℃) |
| color | Clear yellow to brown |
| Odor | Moderate aniline-type. |
| PH | 7.6 (1g/l, H2O, 20℃) |
| Water Solubility | 30 g/L |
| Sensitive | Air Sensitive |
| Merck | 146019 |
| BRN | 741982 |
| Henry's Law Constant | (x 10-5 atm?m3/mol): 1.19 at 25 °C (approximate - calculated from water solubility and vapor pressure) |
| Dielectric constant | 6.0（22℃） |
| Exposure limits | NIOSH REL: TWA 0.5 ppm (2 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 2 ppm (9 mg/m3); ACGIH TLV: TWA 0.5 ppm (adopted). |
| Stability: | Incompatible with strong oxidizing agents. Discolours upon exposure to air. |
| InChI | 1S/C7H9N/c1-8-7-5-3-2-4-6-7/h2-6,8H,1H3 |
| InChIKey | AFBPFSWMIHJQDM-UHFFFAOYSA-N |
| SMILES | CNc1ccccc1 |
| LogP | 1.66 at 20℃ |
| CAS DataBase Reference | 100-61-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Aniline, N-methyl-(100-61-8) |
| EPA Substance Registry System | N-Methylaniline (100-61-8) |
Safety Information
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-33-50/53 |
| Safety Statements | 28-36/37-45-60-61-28A |
| RIDADR | UN 2294 6.1/PG 3 |
| OEB | B |
| OEL | TWA: 0.5 ppm (2 mg/m3) [skin] |
| WGK Germany | 3 |
| RTECS | BY4550000 |
| F | 8 |
| Autoignition Temperature | 500 °C |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214200 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 |
| toxic compounds or compounds which causing chronic effects | |
| Hazard Classifications | Acute Tox. 3 Dermal |
| Acute Tox. 3 Inhalation | |
| Acute Tox. 3 Oral | |
| Aquatic Acute 1 | |
| Aquatic Chronic 1 | |
| Eye Irrit. 2 | |
| STOT RE 2 Oral | |
| Hazardous Substances Data | 100-61-8(Hazardous Substances Data) |
| Toxicity | LD in rabbits (g/kg): 0.28 orally; in rabbits, cats (mg/kg): 24, 24 i.v. (Treon) |
| IDLA | 100 ppm |
Product Application of N-Methylaniline CAS#100-61-8
N-Methylaniline (NMA) serves as a precursor for the synthesis of poly(N-methylaniline)-lignosulfonate (PNMA-LS) composite spheres exhibiting silver-ion adsorption properties. It is also utilized in the fabrication of poly(N-methylaniline) (PNMA) coatings on steel disc electrodes using potentiodynamic, potentiostatic, and galvanostatic electrodeposition methods.
